Hello everyone! Welcome to GoggleDocs’ first video podcast on YouTube.
GoggleDocs are a group of four doctors (and friends!) based in the UK. Our videos will feature a variety of informative yet light-hearted discussions on all things Cardio-Renal-Metabolic (CRM) medicine and beyond…and in our first video we discuss our highlights of CRM medicine from 2020.
————VIDEO CONTENT————-
00:00:00 – Intro
00:02:12 – Guidelines & License Changes
00:17:48 – Key Scientific Trials
00:36:41 – New Products
00:49:58 – COVID-19 & Diabetes
01:01:00 – Round-up and closing remarks
———-LINK TO REFERENCES———-
1) Guidelines & License Changes:
ADA 2021: https://care.diabetesjournals.org/content/44/Supplement_1/S111
PCDE: https://www.primary-care-diabetes.com/article/S1751-9918(20)30189-3/pdf
KDIGO: https://kdigo.org/wp-content/uploads/2020/10/KDIGO-2020-Diabetes-in-CKD-GL.pdf
Canagliflozin license: https://www.medicines.org.uk/emc/medicine/28400#gref
Dapagliflozin license: https://www.medicines.org.uk/emc/product/7607/smpc
Dulaglutide license: https://www.medicines.org.uk/emc/product/7482/smpc
2) Key scientific trials:
DAPA-CKD: https://www.nejm.org/doi/full/10.1056/NEJMoa2024816
EMPEROR REDUCED: https://www.nejm.org/doi/full/10.1056/NEJMoa2022190
FIDELIO: https://www.nejm.org/doi/full/10.1056/NEJMoa2025845
SCORED: https://www.nejm.org/doi/pdf/10.1056/NEJMoa2030186
SOLOIST: https://www.nejm.org/doi/pdf/10.1056/NEJMoa2030183
VERTIS CV: https://www.nejm.org/doi/full/10.1056/NEJMoa2004967
2) New products:
RYBELSUS (Oral Semaglutide): https://www.medicines.org.uk/emc/product/9748/smpc#gref
BEMPEDOIC ACID: https://www.medicines.org.uk/emc/product/11743/smpc
INCLISIRAN: https://www.novartis.com/news/media-releases/novartis-receives-eu-approval-leqvio-inclisiran-first-class-sirna-lower-cholesterol-two-doses-year
3) COVID-19 and Diabetes:
NHS England Diabetes & COVID mortality data: https://www.england.nhs.uk/publication/type-1-and-type-2-diabetes-and-covid-19-related-mortality-in-england/
PCDS Remote Consultations: https://www.pcdsociety.org/news/details/remote-diabetes-reviews-a-quick-guide-from-the-pcds-
Risk Stratification of Diabetes: https://abcd.care/sites/abcd.care/files/site_uploads/Resources/COVID-19/ABCD-Recovery-Guidance-2020-06-23.pdf
We’d love to hear your comments on this video and suggestions on future episodes 🙂
If you like what you see, please subscribe to our channel – thanks, and see you soon!
Video Rating: / 5
An overview of the presentation, etiologies, and management of diabetic ketoacidosis. Included is a comparison with the hyperosmolar hyperglycemic state (HHS) and a brief discussion of the biochemistry of ketone bodies.
Thumbnail incorporated image of insulin from Blausen.com staff (2014). «Medical gallery of Blausen Medical 2014». WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436.
#insulin #diabetes #dka
Beating Diabetes type 1 and 2 with the help of #14daysnegative herbal remedies was the best thing I have done in my Diabetic journey I am thankful #Drkanayo Peterson after 2
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13:57
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I was admitted to the ER with uncontrollable vomiting with a ketone strip indicating heavy ketones in my urine, due to gastric distress. WBC was 20k no fever. I was treated as an appendicitis patient.My brain was affected I was heavily confused and released after several hours due to covid crowding. My pcp followed up by prescribing anti-vomiting drugs Zofran and Phenergan and scopalomine. patches as my blood pressure went from 200/120 to 90/60 i was tachachardic. Did DKA cause permanent muscle and brain issues?
Very informative data….You can get the point of each topic … Thanks Dr.Strong
Why is there a volume deficit not attributable to free water loss here? Thank you in advance.
I hope I learned this and became a doctor. This disease killed my dad. I miss him.
Love you so much sir.
Very good video I’ve been a hospitalist for 3 years and this was still informative. I wasn’t clear, Did you mention DKA is being treated with sub q insulin? How are they addressing the IVF and are they just using a standard sliding scale?
i would like ur video but its at 420…. nice
1/2 NS – you mean 0,9/2= 0,45% NS?
hi eric many congrats on great teaching videos,,,just a word about hypovolumic hypoNa ,, its physiology is that ketones wash out Na in the urine . its not like they drink plain water,,they are actually prone to osmotic hyper Na ———-tapesh bansal YOUNG INDIA INTENIVIST
Great lecture. Can you shed some light on un-resolving acidemia in DKA? Thanks.
Very informative video. It would be greatly appreciated if you could also include SI units.
Hi, I have seen your Youtube channel and it’s really incredible and your videos are great. I want to have your contact for collaboration. Could you please let me know your email? Thank you so much.
This is so good! I really appreciate the added info on hospital protocol as well as general management
So glad you did this one. Especially since tbe background basic science of the clinical phenomena, when known, are presented.
Such a great video 👏
Amazing thanks ☺️
Thank you Dr Strong so wonderful lecture . So great clinical point and new , Yours are the best lecture in medicine.
Literally yesterday had my clinical rotation on hyperglycemic crises :'v hahaha. Anyways, it will help me review the topic. Thank you Dr Strong!!!!