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Video Summary:
Mechanism of action of SGLT2 inhibitors: They decrease the reabsorption of glucose at the proximal tubule by inhibiting SGLT2, which is the main transporter involved in luminal uptake of the glucose.
● More videos on Insulin and Diabetes
• Mechanism of Insulin Secretion: https://youtu.be/5M7Lj9Fx1_w
• Mechanism of Action of Sulfonylureas and Meglitinide Analogues: https://youtu.be/rz7KJK_EMpA
• Oral Antidiabetic Drugs Classification: https://youtu.be/mMRQiaxkyCM
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DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.
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Sglt2 inhibitors lower glucose as well as insulin levels so that the glucagon pathway is the source of energy which may lead to dka particularly If the diabetic contracts covid and If a novice who gets carried away by the promotion of sglt2 inhibitors handles such cases patient will definitely land up with irreversible Ards and death. The drug should be only reserved for diabetics with reno and cardio complication and should never be prescribed to young diabetics who can be treated with positive anti diabetics. The answer to this is to study the covid deaths in diabetics on sglt2 inhibitors.till date.
I kindly requesting sir you to make video on study state plasma concentration sir